IGFBP7 mediates oxLDL-induced human vascular endothelial cell injury by suppressing the expression of SIRT1
Endothelial cell injury plays an important role in initiating atherosclerotic lesion formation.Insulin-like growth factor binding protein 7 (IGFBP7) is known to modulate the behaviors of tumor-associated endothelial cells.This study was conducted to test whether IGFBP7 is involved in endothelial cell injury during atherosclerosis.Oxidized low-densi